Daily Archives: November 22, 2018
Efficacy and Safety of Abrilumab in a Randomized, Placebo-Controlled Trial for Moderate to Severe Ulcerative Colitis
α4β7 integrin is a validated target in inflammatory bowel disease. This randomized, phase 2b, placebo-controlled, double-blind study evaluated the efficacy and safety of the anti-α4β7 antibody abrilumab in patients with moderate-to-severe ulcerativ… Continue reading
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Histone Demethylase JMJD2D Interacts with Beta-catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice
Wnt signaling contributes to development of colorectal cancer (CRC). We studied interactions between lysine demethylase 4D (KDM4D or JMJD2D) and beta-catenin, a mediator of Wnt signaling, in CRC cell lines and the effects on tumor formation in mice. Continue reading
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Beyond Hospital Rankings: How Do We Measure Academic Strength in Gastroenterology/Hepatology Divisions?
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Atg5 in pancreatic tumorigenesis and progression: dosage matters
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High mucosal plasma cell numbers and low serum TREM-1 levels may predict non-responsiveness to anti-TNF therapy in IBD
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How to approach a patient with refractory or recurrent benign esophageal stricture
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Reply to GASTRO-D-00880 and GASTRO-D-01809
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New and Old Biomarkers for Diagnosis and Management of Chronic HBV Infection
Tests to detect the presence and activity of hepatitis B virus (HBV) are the cornerstones of diagnosis and management. Assays that detect or measure serum levels of HB surface antigen, HB surface antibody, and HB core antibody are used to identify pati… Continue reading
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Reply to “The National Trends in Acute and Chronic Pancreatitis Needs to be Improved,” (Manuscript GASTRO-D-18-00901)
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