Monthly Archives: December 2018

Development of celiac disease is believed to involve the transglutaminase-dependent response of CD4+ T cells toward deamidated gluten peptides in the intestinal mucosa of individuals with specific HLA-DQ haplotypes. We investigated the antigen presenta… Continue reading →

Spontaneous clearance of hepatitis C virus (HCV) occurs in approximately 30% of infected persons and less often in populations of African ancestry. Variants in major histocompatibility complex (MHC) and in interferon lambda genes are associated with sp… Continue reading →

Due to advances in research methods, hepatitis viruses can be visualized in microscopic detail, grown in culture, and characterized fully at the genome level; hepatitis C virus (HCV) infection can be cured with drugs that block the virus’s enzymatic … Continue reading →

For many decades, viral hepatitis has been an important public health threat. Hepatitis viruses infect millions of people worldwide. Chronic infections with hepatitis B virus (HBV), HCV, or HDV are associated with cirrhosis and liver cancer, and are am… Continue reading →