Daily Archives: January 30, 2019
CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T and CD4+ T cell-Dependent Control of Senescence
Inflammation in the liver provokes fibrosis but inflammation is also important for tumor surveillance. Inhibitors of chemokine pathways, such as CXCL16 and CXCR6 regulation of lymphocyte trafficking, are being tested as anti-fibrotic agents, but their … Continue reading
RNA Genetic Testing Identifies Germline Pathogenic MSH2 Tandem Duplications in Lynch Syndrome Patients
Correction of Defective T-regulatory Cells From Patients With Crohn’s Disease by Ex Vivo Ligation of Retinoic Acid Receptor Alpha
Crohn’s disease (CD) is characterized by an imbalance of effector and regulatory T cells in the intestinal mucosa. The efficacy of anti-adhesion therapies led us to investigate whether impaired trafficking of T-regulatory (Treg) cells contributes to … Continue reading
Transplant Center performs 500th lung transplant
Alabama resident Andy Bolden spent much of the last five years on the couch, having difficulty doing something many people take for granted — breathing. Thanks to a lung transplant on Nov. 18, 2018, he can breathe normally again. It was a landmark for… Continue reading
Patient messages help predict medication adherence
Around two-thirds of patients treated for breast cancer will have had hormone-sensitive tumors and, after their initial treatment, will be advised to undergo hormone therapy for five to 10 years to prevent recurrence. But around half of these patients … Continue reading