Daily Archives: February 8, 2019

The most common complication following a proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the development of pouchitis, however gaps exist in our understanding of the clinical course of pouch-related disorders. We used data from a cohort of … Continue reading →

Patients with Crohn’s disease (CD) have increased risk of developing colorectal cancer (CRC) compared with the background population. In our previous study, CRC associated with CD in Japan mostly arises in anorectal region, while colonic cancer is pr… Continue reading →

Ileocolic resection (ICR) is the most common surgical procedure for Crohn’s disease (CD). Reconstruction is most commonly achieved with stapled side-to-side (SSTS) or hand-sewn (HS) ileocolic anastomosis (ICA), depending on tissue quality, surgeon ex… Continue reading →

Mucosal barrier dysfunction to luminal microbes plays a crucial role in the development of intestinal inflammation in Crohn’s disease (CD). Recently, an inflammatory form of intestinal epithelial cell (IEC) death resulting from innate immune activati… Continue reading →

Structural brain changes in gray and white matter have been found in adults with Crohn’s disease (CD). In adults, increased disease activity has also been associated with decreased cognitive performance. We have shown similar effects for pediatric CD… Continue reading →

Up to 30% of patients with ulcerative colitis (UC) require colectomy, but whether racial disparities exist in hospital presentation, operation choice, and post-operative outcomes remains unknown. Continue reading →

South Asians (SA) have recently been identified as having a rapidly rising incidence and prevalence of inflammatory bowel disease (IBD) throughout the world. However, longitudinal phenotypic studies of SA living in the United States remain scarce. Continue reading →

Ileocolic resection (ICR) is the most common surgical procedure for Crohn’s disease (CD). Anastomotic construction is most commonly achieved with stapled side-to-side (SSTS) or hand-sewn end-to-end anastomosis (ETE), with the decision often made by t… Continue reading →

Patients with ulcerative colitis (UC) are at increased risk of developing colorectal cancer. Independent risk factors include age, gender, extent and duration of disease activity, concurrent primary sclerosing cholangitis, a family history of sporadic … Continue reading →

Inflammatory bowel disease is considered a global disease in the 21st century. Studies worldwide have shown an increase in incidence in paediatric population. The aim of the study was to detect the rising incidence of IBD in paediatric population (appr… Continue reading →