Mucosal healing is widely recognized as the gold standard for assessing Crohn’s disease (CD) activity. Existing indices for assessing mucosal healing such as the simple endoscopic score for CD (SES-CD) are cumbersome and not commonly used in practice. An easy endoscopic score is needed for large clinical registries and pragmatic trials. We developed the physician global assessment colonoscopy score (PGA-CS), a new streamlined score to facilitate standardization of recording mucosal healing assessment.