Monthly Archives: March 2019

Bariatric surgery might reduce overall mortality from obesity. We investigated whether survival times of patients who have undergone bariatric surgery are similar to those of the general population levels and are longer than in obese individuals who di… Continue reading →

Irritable bowel syndrome (IBS) is common but difficult to treat. Altering the gut microbiota has been proposed as a strategy for treatment of IBS, but the association between the gut microbiome and IBS symptoms has not been well established. We perform… Continue reading →

Leaders of Vanderbilt University Medical Center today announced plans to purchase Tennova Healthcare-Lebanon, a two-campus facility licensed for 245 beds, from subsidiaries of Community Health Systems, Inc. A definitive agreement has been signed for th… Continue reading →

Pathogenic germline variants in CDH1 are associated with risk for diffuse gastric cancer (DGC) and lobular breast cancer. The reported high incidence of DGC and limited sensitivity of endoscopy in detection have prompted recommendation for total prophy… Continue reading →

Reduced gastrointestinal (GI) motility is a feature of disorders associated with intestinal dysbiosis and loss of beneficial microbes. It is not clear how consumption of beneficial commensal microbes, marketed as probiotics, affects the enteric nervous… Continue reading →

The American Cancer Society has recommended initiating colorectal cancer (CRC) screening at age 45 years instead of 50 years. We estimated the cost effectiveness and national effects of adopting this recommendation. Continue reading →

One strategy to treat chronic hepatitis B virus (HBV) infection could be to increase the functions of virus-specific T cells. We performed a multicenter phase 2 study to evaluate the safety and efficacy of GS-4774, a yeast-based therapeutic vaccine eng… Continue reading →