Daily Archives: March 5, 2019

Bile acids (BAs) are synthesized from the liver to aid in fat and fat-soluble vitamin solubilization and absorption. Approximately 95% of the unbound BAs are reabsorbed via the ileal BA transporter and transported through the portal circulation to the… Continue reading →

The importance of Barrett’s esophagus lies in its potential for malignant conversion to invasive esophageal adenocarcinoma (EA), a cancer with an extremely poor prognosis. Although a relatively rare event, with a progression risk of <1 per 300 patients with nondysplastic Barrett’s per year,1,2 esophageal cancer deaths contribute a nontrivial excess lifetime mortality risk for such patients. The lack of successful treatments for advanced disease indicate that prevention is a highly important strategy to improve outcomes. Continue reading →

In today’s health care economy, physician leaders are required to build programs that fill the unmet needs of their patient population in a cost-effective manner.1 The practice of gastroenterology has numerous areas of specialization that provide inn… Continue reading →

Click B, Pinky P, Hickey T, et al. Association of colonoscopy adenoma findings with long-term colorectal cancer incidence. JAMA 2018;319:2021–2031. Continue reading →

A single-center, randomized trial showed that the combination of fecal microbiota transplantation and vancomycin resulted in more clinical resolution compared with either fidaxomicin or vancomycin alone. Continue reading →

Simon TG, Ma Y, Ludvigsson JF, et al. Association between aspirin use and risk of hepatocellular carcinoma. JAMA Oncol 2018;4:1683–1690. Continue reading →

Acute-on-chronic liver failure (ACLF) is an extremely relevant clinical entity, recently characterized by the Canonic Study (2013),1,2 consisting of the simultaneous development of acute decompensation (ascites, encephalopathy, and/or gastrointestinal … Continue reading →