Daily Archives: March 26, 2019

A prospective, multicenter study showed the usefulness of a novel balloon mucosal impedance catheter in differentiating esophageal diseases, including gastroesophageal reflux disease and eosinophilic esophagitis. Continue reading →

After the breakthrough of direct antiviral agents (DAA) for hepatitis C virus (HCV) treatment, a seminal study from the Barcelona Clinic Liver Cancer team suggested a potential increase of hepatocellular carcinoma (HCC) recurrence (“a note of caution… Continue reading →

Chronic damage to hepatocytes causes persistent inflammation, leading to chronic hepatitis, liver cirrhosis, and eventually hepatocellular carcinoma (HCC).1 Along with the concept that the HCC microenvironment is composed of a heterogeneous mixture of … Continue reading →

Hepatocellular carcinoma (HCC) is the sixth most commonly diagnosed cancer and the fourth leading cause of death worldwide.1 Until recently, treatment options for advanced disease have been limited. Sorafenib—a tyrosine kinase inhibitor (TKI) targeti… Continue reading →

We are saddened by the loss of our wonderful colleague and friend, Wendy Atkin, who passed away in October 2018. Wendy was neither a gastroenterologist nor a surgeon, but her work on colorectal cancer (CRC) screening, surveillance, and quality have had… Continue reading →

Colorectal cancer (CRC) has a significant impact on public health owing to its high incidence, morbidity, and mortality.1 It is the third most common cancer in men and second in women, and in most countries the second leading cause of cancer-related de… Continue reading →

Cremonesi E, Governa V, Garzon JFG, et al. Gut microbiota modulate T cell trafficking into human colorectal cancer Gut 2018;67:1984–1994. Continue reading →

Pancreatic cancer is a terrible disease. Patients often become seriously ill within months of diagnosis and <10% of patients are cured of their cancer. To make matters worse, the number of cases of pancreatic cancer continues to increase each year, and it will soon become the second leading cause of cancer death in the United States.1 Thus, even in a time of hyperbole, one can reasonably say that dealing with pancreatic cancer is a matter of great urgency if we are to continue progress in reducing cancer-related mortality. Continue reading →

Owen RP, White MJ, Severson DT, et al. Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oesophageal submucosal glands. Nature Comms 2018;9:4261–4272. Continue reading →

Corpechot C, Chazouillères O, Rousseau A, et al. A placebo-controlled trial of bezafibrate in primary biliary cholangitis. N Engl J Med 2018;378:2171–2181. Continue reading →