Daily Archives: April 25, 2019

Presentation of the Julius M. Friedenwald Medal to John I. Allen

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Endoplasmic Reticulum Stress-induced Upregulation of STARD1 Promotes Acetaminophen-induced Acute Liver Failure

Acetaminophen overdose is a major cause of acute liver failure (ALF). Mitochondrial SH3BP5 (also called SAB) and phosphorylation of JNK mediate the hepatotoxic effects of acetaminophen. We investigated the involvement of steroidogenic acute regulatory … Continue reading

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