Daily Archives: May 9, 2019

Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia

Posted on May 9, 2019 by Gastroenterology Journal

Most pancreatic ductal adenocarcinomas (PDACs) express an activated form of KRAS, become hypoxic and dysplastic, and are refractory to chemo- and radiation-therapies. To survive in the hypoxic environment, PDAC cells upregulate enzymes and transporters… Continue reading →

Posted in News | Comments Off on Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia

Endoscopic surveillance of Barrett’s esophagus using volumetric laser endomicroscopy with artificial intelligence image enhancement

Posted on May 9, 2019 by Gastroenterology Journal
Posted in News | Comments Off on Endoscopic surveillance of Barrett’s esophagus using volumetric laser endomicroscopy with artificial intelligence image enhancement

A Rare Cause of Paradoxical Nausea and Abdominal Pain

Posted on May 9, 2019 by Gastroenterology Journal
Posted in News | Comments Off on A Rare Cause of Paradoxical Nausea and Abdominal Pain

Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Non-Alcoholic Steatohepatitis

Posted on May 9, 2019 by Gastroenterology Journal

We studied the role of interleukin 11 (IL11) signaling in the pathogenesis of nonalcoholic steatohepatitis using hepatic stellate cells (HSCs), hepatocytes, and mouse models of non-alcoholic steatohepatitis (NASH). Continue reading →

Posted in News | Comments Off on Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Non-Alcoholic Steatohepatitis

A Fist-Sized Radiographic Consolidation in a Man Suffering From Difficulty Swallowing

Posted on May 9, 2019 by Gastroenterology Journal
Posted in News | Comments Off on A Fist-Sized Radiographic Consolidation in a Man Suffering From Difficulty Swallowing

Amino Acid Substitutions in Genotype 3a Hepatitis C Virus Polymerase Protein Affect Responses to Sofosbuvir

Posted on May 9, 2019 by Gastroenterology Journal

Sofosbuvir is a frequently used pan-genotype inhibitor of hepatitis C virus (HCV) polymerase. This drug eliminates most chronic HCV infections and resistance-associated substitutions in the polymerase are rare. However, HCV genotype 3 responds slightly… Continue reading →

Posted in News | Comments Off on Amino Acid Substitutions in Genotype 3a Hepatitis C Virus Polymerase Protein Affect Responses to Sofosbuvir