Daily Archives: May 16, 2019
Use of Phosphodiesterase 5 Inhibitors Associates With Risk of Colorectal Cancer in Men With Benign Colorectal Neoplasms
Phosphodiesterase 5 (PDE5) inhibitors have been proposed to have chemopreventative effects on colorectal cancer (CRC), although data are needed from population-based studies. We performed a nationwide cohort study to investigate the association between… Continue reading
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Surgery versus endoscopy for infected necrotizing pancreatitis: a fair comparison?
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Right-Sided Location Not Associated with Missed Colorectal Adenomas in an Individual-Level Reanalysis of Tandem Colonoscopy Studies
Interval cancers occur more frequently in the right colon. One reason could be that right-sided adenomas are frequently missed in colonoscopy examinations. We reanalyzed data from tandem colonoscopies to assess adenoma miss rates in relation to locatio… Continue reading
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RNA-Binding Protein HuR Regulates Paneth Cell Function by Altering Membrane Localization of TLR2 via Posttranscriptional Control of CNPY3
Paneth cells secrete antimicrobial proteins including lysozyme via secretory autophagy as part of the mucosal protective response. The ELAV like RNA-binding protein 1 (ELAVL1, also called HuR) regulates stability and translation of mRNAs and many aspec… Continue reading
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