Monthly Archives: May 2019

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Our New President—Hashem El-Serag, MD, MPH, AGAF

It is an honor and a privilege to introduce Dr Hashem El-Serag, who will become the 114th president of the American Gastroenterological Association (AGA) Institute in May 2019. This biography covers Hashem’s journey that started from an oppressed to… Continue reading

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Use of Phosphodiesterase 5 Inhibitors Associates With Risk of Colorectal Cancer in Men With Benign Colorectal Neoplasms

Phosphodiesterase 5 (PDE5) inhibitors have been proposed to have chemopreventative effects on colorectal cancer (CRC), although data are needed from population-based studies. We performed a nationwide cohort study to investigate the association between… Continue reading

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Surgery versus endoscopy for infected necrotizing pancreatitis: a fair comparison?

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Right-Sided Location Not Associated with Missed Colorectal Adenomas in an Individual-Level Reanalysis of Tandem Colonoscopy Studies

Interval cancers occur more frequently in the right colon. One reason could be that right-sided adenomas are frequently missed in colonoscopy examinations. We reanalyzed data from tandem colonoscopies to assess adenoma miss rates in relation to locatio… Continue reading

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RNA-Binding Protein HuR Regulates Paneth Cell Function by Altering Membrane Localization of TLR2 via Posttranscriptional Control of CNPY3

Paneth cells secrete antimicrobial proteins including lysozyme via secretory autophagy as part of the mucosal protective response. The ELAV like RNA-binding protein 1 (ELAVL1, also called HuR) regulates stability and translation of mRNAs and many aspec… Continue reading

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Understanding the current evidence on proton pump inhibitor use and bone health

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Hot polypectomy: a cautionary tale?

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RE: Risk of post-polypectomy bleeding with uninterrupted clopidogrel therapy in an industry-independent, double blind, randomized, trial

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EUS-Guided Drainage for Infected Necrotizing Pancreatitis: Better than Surgery But Still Lacking Treatment Protocol Standardization

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