Daily Archives: June 5, 2019
Cross Validation of the Monoclonal Antibody Das-1 in Identification of High-risk Mucinous Pancreatic Cystic Lesions
Although pancreatic cystic lesions (PCLs) are frequently and incidentally detected, it is a challenge to determine their risk of malignancy. In immunohistochemical and ELISA analyses of tissue and cyst fluid from pancreatic intraductal papillary mucino… Continue reading
Analysis of Transcriptionally Active Bacteria Throughout the Gastrointestinal Tract of Healthy Individuals
The microbiome varies along the human gastrointestinal (GI) tract with exposure to luminal and mucosal factors. We analyzed active bacterial communities at 8 locations along the GI tract using high-throughput sequencing techniques. Continue reading
Intraductal Papillary Mucinous Neoplasms Arise from Multiple Independent Clones, Each With Distinct Mutations
Intraductal papillary mucinous neoplasms (IPMNs) are lesions that can progress to invasive pancreatic cancer and an important system for studies of pancreatic tumorigenesis. We performed comprehensive genomic analyses of entire IPMNs to determine the d… Continue reading
Vedolizumab Induces Endoscopic and Histologic Remission in Patients With Crohn’s Disease
We evaluated the ability of vedolizumab to induce endoscopic and histologic remission in patients with Crohn’s disease (CD). Continue reading
AMA grant to enhance resident training across nation
Vanderbilt University Medical Center is one of eight award recipients that will receive funding from the American Medical Association (AMA) as part of its new Reimagining Residency initiative. Continue reading
Immunotherapy helping 87-year-old man stay on the job
Nine years after being diagnosed with metastatic lung cancer, Roszell Mack Jr., 87, goes into the office every day. Immunotherapy is helping him to continue going to his job on a Kentucky horse farm.
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VUMC joins international effort to speed vaccine development
Vanderbilt University Medical Center has joined an international effort to streamline and accelerate development of vaccines and other treatments against a growing worldwide surge of deadly and debilitating viral infections. Continue reading