Daily Archives: July 20, 2019

Development and Validation a Magnetic Resonance Index for Assessing Fistulas in Patients With Crohn’s Disease

Posted on July 20, 2019 by Gastroenterology Journal

There is no validated magnetic resonance imaging (MRI) index for assessment of perianal fistulas in patients with Crohn’s disease (CD). We developed and internally validated a new instrument. Continue reading →

Posted in News | Comments Off on Development and Validation a Magnetic Resonance Index for Assessing Fistulas in Patients With Crohn’s Disease

Small-molecule inhibitors of cyclophilins block opening of the mitochondrial permeability transition pore and protect mice from hepatic ischemia–reperfusion injury

Posted on July 20, 2019 by Gastroenterology Journal

Hepatic ischemia–reperfusion injury is a complication of liver surgery that involves mitochondrial dysfunction resulting from mitochondrial permeability transition pore (mPTP) opening. Cyclophilin D (PPIF or CypD) is a peptidyl-prolyl cis-trans isome… Continue reading →

Posted in News | Comments Off on Small-molecule inhibitors of cyclophilins block opening of the mitochondrial permeability transition pore and protect mice from hepatic ischemia–reperfusion injury