Monthly Archives: July 2019

Improving safety of drugs given during pregnancy goal of collaboration

A 19-year-old student at Vanderbilt University is leading a multi-institutional collaboration to identify — using computer-based approaches — drugs that can be prescribed safely to pregnant women without harming the fetus. Continue reading

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Meena Madhur receives Presidential Early Career Award

The award, established in 1996, is the highest honor bestowed by the U.S. government on outstanding scientists and engineers in the early stages of their independent research careers, according to a news release from the White House. Continue reading

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Development and Validation a Magnetic Resonance Index for Assessing Fistulas in Patients With Crohn’s Disease

There is no validated magnetic resonance imaging (MRI) index for assessment of perianal fistulas in patients with Crohn’s disease (CD). We developed and internally validated a new instrument. Continue reading

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Small-molecule inhibitors of cyclophilins block opening of the mitochondrial permeability transition pore and protect mice from hepatic ischemia–reperfusion injury

Hepatic ischemia–reperfusion injury is a complication of liver surgery that involves mitochondrial dysfunction resulting from mitochondrial permeability transition pore (mPTP) opening. Cyclophilin D (PPIF or CypD) is a peptidyl-prolyl cis-trans isome… Continue reading

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Emergencies in an advanced stage Parkinson’s disease patient

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An Unusual Case of Esophagitis

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Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases

Altered interactions between the mucosal immune system and intestinal microbiota contribute to pathogenesis of inflammatory bowel diseases (IBD). It is not clear how inhibitors of cytokines, such as antagonists of tumor necrosis factor (anti-TNF), affe… Continue reading

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Natural language commands vital to making EHRs seamless, “delightful”

Yaa Kumah-Crystal, MD, MPH, MS, self-describes as an early adopter of technology who is seizing on the fast embrace of natural language recognition systems — i.e. Siri and Alexa — to usher in an era of medicine where the tech is just as responsive. Continue reading

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Alzheimer’s is more common in women than in men; these Vanderbilt researchers may have discovered why

The abnormal accumulation of proteins in the brain is a biological marker for Alzheimer’s disease, but the ways in which these proteins spread may help explain why the prevalence of Alzheimer’s is higher in women than in men. Continue reading

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Megan Rasmussen named Vanderbilt Prize Student Scholar

She will receive a $1,000 cash prize and will be mentored by the winner of the 2019 Vanderbilt Prize in Biomedical Research, Harvard Medical School geneticist Christine Seidman, MD. Rasmussen is a doctoral candidate in the lab of Vivian Gama, PhD, assi… Continue reading

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