Daily Archives: August 20, 2019

Can retrospective studies confirm the causation of drug induced liver injury?

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The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 in and Promotes Tumorigenesis in Mice

The histone lysine demethylase 3A (KDM3A) demethylates demethylates H3K9me1 and H3K9Me2 to increase gene transcription and is upregulated in tumors, including pancreatic tumors. We investigated its activities in pancreatic cancer cell lines and its reg… Continue reading

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Neonatal life events and the risk of inflammatory bowel disease

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Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on single-cell Transcriptome Analyses

It has been a challenge to develop fully functioning cells from human pluripotent stem cells (hPSCs). We investigated how activation of hedgehog signaling regulates derivation of enteric neural crest (NC) cells from hPSCs. Continue reading

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Reply to “Incidence and Etiology of Drug-Induced Liver Injury in Mainland China”

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Eradication of Helicobacter pylori in Children Restores the Structure of the Gastric Bacterial Community to That of Non-infected Children

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RE: Incidence and Etiology of Drug-Induced Liver Injury in Mainland China

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Events Early in Life, But Not The Neonatal Period, Affect Risk For Later Development of Inflammatory Bowel Disease

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Friend or Foe in IBD Pathogenesis: Not All Infections are Equal

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Information for Authors and Readers

Gastroenterology is the premiere journal in the field of gastrointestinal disease and is led by an internationally renowned board of editors. As the official journal of the AGA Institute, Gastroenterology delivers up-to-date and authoritative coverag… Continue reading

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