Daily Archives: September 4, 2019

Prophylactic clip closure clarified: the question is not whether to clip, but when

Posted on September 4, 2019 by Gastroenterology Journal
Posted in News | Comments Off on Prophylactic clip closure clarified: the question is not whether to clip, but when

Ca2+ Influx Channel Inhibitor SARAF Protects Mice From Acute Pancreatitis

Posted on September 4, 2019 by Gastroenterology Journal

Pancreatitis is characterized by increased influx of Ca2+ into acinar cells, by unknown mechanisms. Inhibitors of Ca2+ influx channels could be effective in treating acute pancreatitis, but these have deleterious side effects that can result in death. … Continue reading →

Posted in News | Comments Off on Ca2+ Influx Channel Inhibitor SARAF Protects Mice From Acute Pancreatitis

Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients With Ulcerative Colitis

Posted on September 4, 2019 by Gastroenterology Journal

Interleukin 23 (IL23) contributes to pathogenesis of ulcerative colitis (UC). We investigated the effects of mirikizumab, a monoclonal antibody against the p19 subunit of IL23, in a phase 2 study of patients with UC. Continue reading →

Posted in News | Comments Off on Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients With Ulcerative Colitis