Daily Archives: November 21, 2019
Use of Family History and Genetic Testing to Determine Risk of Colorectal Cancer
Approximately 35% of patients with colorectal cancer (CRC) have a family history of the disease, due to genetic factors, common exposures, or both. Some families with a history of CRC carry genetic variants that cause CRC with high or moderate penetran… Continue reading
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Deep-Learning System Detects Neoplasia in Patients With Barrett’s Esophagus With Higher Accuracy Than Endoscopists in a Multi-Step Training and Validation Study with Benchmarking
We aimed to develop and validate a deep-learning computer-aided detection (CAD) system, suitable for use in real time in clinical practice, to improve endoscopic detection of early neoplasia in patients with Barrett’s esophagus (BE). Continue reading
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HNF4 Regulates Fatty Acid Oxidation and is Required for Renewal of Intestinal Stem Cells in Mice
Functions of intestinal stem cells (ISCs) are regulated by diet and metabolic pathways. Hepatocyte nuclear factor 4 (HNF4) are transcription factors that bind fatty acids. We investigated how HNF4 transcription factors regulate metabolism and their fun… Continue reading
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How to approach burnout among GI fellows
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