Daily Archives: December 19, 2019

Cumulative Burden of Colorectal Cancer-Associated Genetic Variants is More Strongly Associated With Early-onset vs Late-onset Cancer

Early-onset colorectal cancer (CRC, in persons younger than 50 years old) is increasing in incidence; yet, in the absence of a family history of CRC, this population lacks harmonized recommendations for prevention. We aimed to determine whether a polyg… Continue reading

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Prevalence of Gastroesophageal Reflux Disease and Proton Pump Inhibitor-Refractory Symptoms

There are few data on the prevalence of gastroesophageal reflux disease (GERD) in the United States. We performed a population-based study to determine the prevalence of GERD symptoms and persistent GERD symptoms despite use of proton pump inhibitors (… Continue reading

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A new blood biomarker of endoscopic disease activity: a step forward in the treat-to-target paradigm for Crohn’s disease?

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Most Patients With Celiac Disease on Gluten-free Diets Consume Measurable Amounts of Gluten

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Identification and Characterization of Unique Neutralizing Antibodies to Mouse EGF Receptor

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