Daily Archives: January 8, 2020

Microscopic Colitis and Risk of Inflammatory Bowel Disease in a Nationwide Cohort Study

Microscopic colitis shares pathogenetic mechanisms with inflammatory bowel disease (IBD). We studied the association between microscopic colitis and risk of incident IBD using data from a nationwide cohort study. Continue reading

Posted in News | Comments Off on Microscopic Colitis and Risk of Inflammatory Bowel Disease in a Nationwide Cohort Study

Safety of Janus Kinase Inhibitors in Patients with Inflammatory Bowel Diseases or Other Immune-mediated Diseases: a Systematic Review and Meta-Analysis

Inhibitors of Janus kinases (JAKs) are being developed for treatment of inflammatory bowel diseases and other immune-mediated diseases. Tofacitinib is effective in treatment of ulcerative colitis, but there are safety concerns. We performed a systemati… Continue reading

Posted in News | Comments Off on Safety of Janus Kinase Inhibitors in Patients with Inflammatory Bowel Diseases or Other Immune-mediated Diseases: a Systematic Review and Meta-Analysis

Infliximab Use in a Child with Ulcerative Colitis and Prior in utero Exposure to Infliximab

Posted in News | Comments Off on Infliximab Use in a Child with Ulcerative Colitis and Prior in utero Exposure to Infliximab

Causes of Post-colonoscopy Colorectal Cancers Based on World Endoscopy Organization System of Analysis

Lay Summary: Some people develop colorectal cancer after a colonoscopy in which a cancer was not detected. Forty-three percent of delays in detection occurred in high-risk patients. We analyzed reasons for the delayed diagnoses, and found 89% to be avo… Continue reading

Posted in News | Comments Off on Causes of Post-colonoscopy Colorectal Cancers Based on World Endoscopy Organization System of Analysis

Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

Lynch syndrome is caused by alterations in a specific group of genes. Patients with different types of genetic alterations develop adenomas and CRC at different rates, and tumors have specific genetic features. Continue reading

Posted in News | Comments Off on Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

Monkey in the middle: dynamics of interspecies antibody responses

Posted in News | Comments Off on Monkey in the middle: dynamics of interspecies antibody responses