Daily Archives: January 20, 2020
Precision therapy in RAS mutant colorectal cancer
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Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity but Develop Fewer Tumors Following Chronic Liver Injury
Polyploid hepatocytes with whole-genome duplications are commonly found in the liver but their importance is not known. Increasing the number of polyploid hepatocytes in mice reduced development of liver tumors without compromising tissue regeneration … Continue reading
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Association Between Sulfur-Metabolizing Bacterial Communities in Stool and Risk of Distal Colorectal Cancer in Men
Diets high in processed meats and low-calorie drinks, and low in vegetables and legumes, can increase the number of sulfur-metabolizing microbes in the colon, which increase risk for colorectal cancer. Continue reading
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High Serum Levels of Cholesterol Increase Anti-tumor Functions of Nature Killer Cells and Reduce Growth of Liver Tumors in Mice
High blood levels of cholesterol increase the anti-tumor activities of specific immune cells in mice. Strategies to increase cholesterol activation of these cells might be developed for treatment of liver cancer in patients. Continue reading
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