Monthly Archives: January 2020

Autophagy of Intestinal Epithelial Cells Inhibits Colorectal Carcinogenesis Induced by Colibactin-producing Escherichia coli in ApcMin/+ Mice

Infection with colibactin-producing Escherichia coli promotes autophagy of intestinal epithelial cells, which is required to prevent the carcinogenic effects of these bacteria. Continue reading

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Expression of FFAR2 by Dendritic Cells Prevents Their Expression of IL27 and is Required For Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice

Intestinal microbes and their metabolites affect development of colorectal cancer (CRC). Short-chain fatty acids are metabolites generated by intestinal microbes from dietary fiber. We investigated the mechanisms by which free fatty acid receptor 2 (FF… Continue reading

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Prevalence of Rome IV Functional Bowel Disorders Among Adults in the United States, Canada, and the United Kingdom

Functional bowel disorders, such as irritable bowel syndrome, are common in North America and the United Kingdom. These reduce quality of life and cause many people to seek gastroenterology care. Continue reading

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How should colonoscopy surveillance in Lynch syndrome be performed?

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REPLY TO GASTRO-D-19-02389

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The Complex Role of Trypsin in Pancreatitis

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Rounds: Making “fresh starts” all year

This year I hope you find moments of success and satisfaction in all parts of your life as well as the energy to take on those hard things you know will create real, sustainable progress toward meeting your goals. And when you get overwhelmed, stuck in… Continue reading

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Rothman to succeed Dittus as director of Institute for Medicine and Public Health

Russell Rothman, MD, MPP, professor of Internal Medicine, Pediatrics and Health Policy, Ingram Professor of Integrative and Population Health, and Vice President for Population Health Research, has been named as the new director of the Institute for Me… Continue reading

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Hold the Stuffing weigh-ins through Jan. 17

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Tomorrow’s Comprehensive Spine Grand Rounds to feature West Virginia’s Sanford Emery

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