Daily Archives: February 4, 2020
Stem cell recipient and donor meet in person for first time
Josh Ferris was sitting in a hunting blind on Nov. 15, 2018, the first day of deer season in Michigan and the one-year anniversary of his stem cell donation, when he received an email from Todd Adams of Nashville, the recipient of his life-saving gift…. Continue reading
Innovative Project SEARCH provides good jobs for participants, great employees for VUMC
The program focuses on training young people with intellectual and developmental disabilities for jobs in health care Continue reading
Study links neural circuit with impaired social function
Stimulating neural activity between the amygdala and the nucleus accumbens — a brain region associated with pleasure — impairs social function even though mice find the stimulation rewarding, a new study published by Vanderbilt researchers in “The Jo… Continue reading
Diabetes Prevention Program information sessions set for Feb. 25, 26, 27 and 28
Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data
Esophageal adenocarcinomas (EAC) are heterogeneous and often preceded by Barrett’s esophagus (BE). Many genomic changes have been associated with development of BE and EAC, but little is known about epigenetic alterations. We performed epigenetic analy… Continue reading
Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease
Celiac disease could be treated, and potentially cured, by restoring T-cell tolerance to gliadin. We investigated the safety and efficacy of negatively charged, 500 nm, poly(lactide-co-glycolide) nanoparticles encapsulating gliadin protein (TIMP-GLIA) … Continue reading
GPR30-expressing Gastric Chief Cells do not Dedifferentiate but are Eliminated via PDK-dependent Cell Competition During Development of Metaplasia
Gastric chief cells, a mature cell type that secretes digestive enzymes, have been proposed to be the origin of metaplasia and cancer, through dedifferentiation or trans-differentiation. However, studies supporting this claim have had technical limitat… Continue reading