Daily Archives: February 18, 2020
Rounds: A tagline to remember
Defining personalized care. It’s a tagline that has appeared in our marketing on social media, billboards and even primetime TV. About 1.7 million Middle Tennessee Super Bowl viewers watched Vanderbilt Health ads showcasing this tagline with compelling… Continue reading
Letter to the editor: Prokinetic effects and symptom relief in the pharmacotherapy of gastroparesis
Prostaglandin E2, Produced by Mast Cells in Colon Tissues from Patients with Irritable Bowel Syndrome, Contributes to Visceral Hypersensitivity in Mice
Visceral hypersensitivity is common in patients with irritable bowel syndrome (IBS). We investigated whether inflammatory molecules, such as histamine and proteases, activate prostaglandin-endoperoxide synthase 2 (PTGS2, also called COX2) to increase t… Continue reading
Prevalence and Clinical Features of Inflammatory Bowel Diseases Associated with Monogenic Variants, Identified by Whole-exome Sequencing in 1000 Children at a Single Center
A proportion of infants and young children with inflammatory bowel diseases (IBD) have subtypes associated with a single gene variant (monogenic IBD). We aimed to determine the prevalence of monogenic disease in a cohort of pediatric patients with IBD. Continue reading