Daily Archives: February 24, 2020

P152 EVALUATING THE EFFICACY OF GLUTAMATE CARBOXYPEPTIDASE II (GCPII) INHIBITORS IN “WILD-TYPE” MICE: LESSONS LEARNED FROM THE DEDICATOR OF CYTOKINESIS 2 MUTANT MOUSE

Glutamate carboxypeptidase II (GCPII) is highly upregulated in human IBD and is a therapeutic target under active investigation by our laboratory. We recently published that a spontaneously occurring loss-of-function mutation in dedicator of cytokinesi… Continue reading

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P151 DISRUPTION OF ENDOGENOUS ITACONATE PRODUCTION EXACERBATES EXPERIMENTAL COLITIS

Inflammation is a hallmark of inflammatory bowel disease and alterations in tricarboxylic acid cycle (TCA) metabolism have been identified as major regulators of immune cell phenotype during inflammation and hypoxia. The TCA cycle metabolite, itaconate… Continue reading

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Vanderbilt Health scores with Nashville Soccer Club; complimentary tickets all claimed but discount still available

Nashville Soccer Club and Vanderbilt Health have announced a strategic, multi-year relationship that includes Vanderbilt Health becoming an official sponsor of Nashville SC and the team’s exclusive health care provider. Continue reading

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VUMC Infection Prevention continues to monitor coronavirus situation

As the 2019 Novel Coronavirus (SARS-CoV-2 which causes COVID-19) continues to spread, with new cases reported in, among other places, Italy, Iran, Japan, and South Korea, VUMC continues to monitor the outbreak closely. Continue reading

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United Way and IRS offer tax preparation services to VUMC employees

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Enhance the VUMC experience: Complete all four Defining Personalized Care segments

Defining Personalized Care — Elevating Our Culture of Service is a multiyear initiative designed to help us improve the service we provide our each other, our patients, and their family members. Each segment was designed to build on each other and sho… Continue reading

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VUMC in the news

A roundup of a few recent stories from the press about Vanderbilt University Medical Center. Continue reading

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“Momentum”: Cancer survivor Adam Kindness counts his blessings

Blessings come in all shapes and sizes. Lately, I have been seeing them all around me. Continue reading

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Post-transplant diabetes may be reversible: study

Post-transplantation diabetes mellitus, a common complication of immunosuppressive drugs that are given to prevent transplant rejection, may be reversible and at least partially preventable, researchers at Vanderbilt University Medical Center report. Continue reading

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Today’s Discovery Lecture to feature head and neck cancer expert Jennifer Grandis

Her lecture, “Head and Neck Cancer Precision Medicine,” will begin at 4 p.m. in 208 Light Hall. It is sponsored by the Department of Otolaryngology.
Grandis is the Robert K. Werbe Distinguished Professor in Head and Neck Cancer at the University of Cal… Continue reading

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