Daily Archives: March 13, 2020

PPE training: Surgical mask with reusable goggles

Posted on March 13, 2020 by Gastroenterology Journal

The Department of Infection Prevention offers guidance for putting on and removing personal protective equipment, specific to reusable goggles. Continue reading →

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GERMLINE MUTATIONS IN FAF1 ARE ASSOCIATED WITH HEREDITARY COLORECTAL CANCER

Posted on March 13, 2020 by Gastroenterology Journal

A significant proportion of colorectal cancer (CRC) cases have familial aggregation but little is known about the genetic factors that contribute to these cases. We performed an exhaustive functional characterization of genetic variants associated with… Continue reading →

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MCL1 is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice

Posted on March 13, 2020 by Gastroenterology Journal

Intestinal epithelial homeostasis depends on a tightly regulated balance between intestinal epithelial cell (IEC) death and proliferation. Disruption of factors that promote IEC death result in intestinal inflammation, whereas loss of anti-apoptotic pr… Continue reading →

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Combination of PD1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer

Posted on March 13, 2020 by Gastroenterology Journal

Advanced pancreatic ductal adenocarcinoma (PDAC) is resistant to therapy, including immune checkpoint inhibitors. We evaluated the effects of a neutralizing antibody against programmed cell death 1 (PDCD1, also called PD1) and an agonist of OX40 (provi… Continue reading →

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Estimation of Absolute Risk of Colorectal Cancer Based on Healthy Lifestyle, Genetic Risk, and Colonoscopy Status in a Population-based Study

Posted on March 13, 2020 by Gastroenterology Journal

Estimates of absolute risk of colorectal cancer (CRC) are needed to facilitate communication and better inform the public about the potentials and limits of cancer prevention. Continue reading →

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