Daily Archives: June 20, 2020
AGA Clinical Practice Update on Endoscopic Therapies for Non-Variceal Upper Gastrointestinal Bleeding: Expert Review
The purpose of this AGA Institute Clinical Practice Update is to review the available evidence and expert recommendations regarding the use of endoscopic therapies in treating patients with non-variceal upper GI bleeding. Continue reading
Adherence of infusible biologics during the time of COVID-19 among patients with Inflammatory Bowel Disease: A nationwide VA cohort study
The inhibitory PVRL1/PVR/TIGIT axis in immune therapy for HCC
Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface
The protease plasmin is an important wound healing factor, but it is not clear how it affects gastrointestinal infection-mediated damage, such as that resulting from Clostridioides difficile. We investigated the role of plasmin in C difficile-associate… Continue reading
IRE1A Stimulates Hepatocyte-derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis
Endoplasmic reticulum to nucleus signaling 1 (ERN1, also called IRE1A) is a sensor of the unfolded protein response that is activated in livers of patients with nonalcoholic steatohepatitis (NASH). Hepatocytes release ceramide-enriched inflammatory ext… Continue reading