Monthly Archives: June 2020
Impact of Pre-existing Chronic Liver Disease on the Outcome of Patients with COVID-19 Disease
Impact of medication discontinuation on patients with inflammatory bowel disease during the COVID-19 outbreak
TNFα-antagonist use and mucosal inflammation are associated with increased intestinal expression of SARS-CoV-2 host protease TMPRSS2 in patients with inflammatory bowel disease
Therapeutic decisions in inflammatory bowel disease in the SARS-Cov-2 pandemic
Human Pluripotent Stem Cell-Derived Organoids as Models of Liver Disease
There are few in vitro models for studying the 3-dimensional interactions among different liver cell types during organogenesis or disease development. We aimed to generate hepatic organoids that comprise different parenchymal liver cell types and have… Continue reading
The Transcription co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation into Enterocyte vs Secretory Lineages
Notch signaling maintains intestinal stem cells (ISCs). When ISCs exit the niche, Notch signaling among early progenitor cells at position +4/5 regulates their specification toward secretory vs enterocyte lineages (binary fate). The transcription facto… Continue reading
Bariatric Surgery Provides Long-term Resolution of Nonalcoholic Steatohepatitis and Regression of Fibrosis
Studies are needed to determine the long-term effects of bariatric surgery for patients with nonalcoholic steatohepatitis (NASH). We evaluated sequential liver biopsies, collected the time of bariatric surgery and 1 and 5 years later, to assess the lon… Continue reading
SEVERE IBD FLARES AND COVID-19: EXPAND THE GASTROENTEROLOGY-SURGERY TEAM TO INCLUDE AN INFECTIOUS DISEASE SPECIALIST
Vanderbilt University announces 2020-2021 campus plan
Today, Incoming Chancellor Daniel Diermeier and Interim Chancellor and Provost Susan Wente announced Vanderbilt’s plan for the 2020-2021 academic year and their return to in-person classes. Continue reading