Monthly Archives: June 2020

Impact of Pre-existing Chronic Liver Disease on the Outcome of Patients with COVID-19 Disease

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Impact of medication discontinuation on patients with inflammatory bowel disease during the COVID-19 outbreak

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TNFα-antagonist use and mucosal inflammation are associated with increased intestinal expression of SARS-CoV-2 host protease TMPRSS2 in patients with inflammatory bowel disease

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Therapeutic decisions in inflammatory bowel disease in the SARS-Cov-2 pandemic

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Human Pluripotent Stem Cell-Derived Organoids as Models of Liver Disease

There are few in vitro models for studying the 3-dimensional interactions among different liver cell types during organogenesis or disease development. We aimed to generate hepatic organoids that comprise different parenchymal liver cell types and have… Continue reading

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The Transcription co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation into Enterocyte vs Secretory Lineages

Notch signaling maintains intestinal stem cells (ISCs). When ISCs exit the niche, Notch signaling among early progenitor cells at position +4/5 regulates their specification toward secretory vs enterocyte lineages (binary fate). The transcription facto… Continue reading

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Bariatric Surgery Provides Long-term Resolution of Nonalcoholic Steatohepatitis and Regression of Fibrosis

Studies are needed to determine the long-term effects of bariatric surgery for patients with nonalcoholic steatohepatitis (NASH). We evaluated sequential liver biopsies, collected the time of bariatric surgery and 1 and 5 years later, to assess the lon… Continue reading

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SEVERE IBD FLARES AND COVID-19: EXPAND THE GASTROENTEROLOGY-SURGERY TEAM TO INCLUDE AN INFECTIOUS DISEASE SPECIALIST

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Vanderbilt University announces 2020-2021 campus plan

Today, Incoming Chancellor Daniel Diermeier and Interim Chancellor and Provost Susan Wente announced Vanderbilt’s plan for the 2020-2021 academic year and their return to in-person classes. Continue reading

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Courtyard Cafe announces this week’s specials

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