Daily Archives: September 18, 2020
DDIT4 licenses only healthy cells to proliferate during injury-induced metaplasia
In stomach, metaplasia can arise from differentiated chief cells that become mitotic via paligenosis, a stepwise program. In paligenosis, mitosis initiation requires reactivation of the cellular energy hub mTORC1 after initial mTORC1 suppression by DNA… Continue reading
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Population-level configurations of gut mycobiome across six ethnicities in urban and rural China
Beyond bacteria, the human gastrointestinal tract is host to a vast diversity of fungi, collectively known as the gut mycobiome. Little is known of the impact of geography, ethnicity and urbanization on the gut mycobiome at a large population level. We… Continue reading
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