Irritable bowel syndrome (IBS) is a common, symptom-based condition that has negative effects on quality of life and costs healthcare systems billions of dollars each year. Until recently, management of IBS has focused on over the counter and prescription medications that reduce symptoms in fewer than half of patients. Patients have increasingly sought natural solutions for their IBS symptoms. However, behavioral techniques and dietary modification can be effective in treatment of IBS. Behavioral interventions include gastrointestinal-focused cognitive behavioral therapy and gut-directed hypnotherapy, to modify interactions between the gut and the brain.