Daily Archives: November 27, 2020
Cancer and the Microbiome: Influence of the commensal microbiota on cancer, immune responses, and immunotherapy
The commensal microbiota has been implicated in the regulation of a diverse array of physiological processes, both within the gastrointestinal tract and at distant tissue sites. Cancer is no exception, and distinct aspects of the microbiota have been r… Continue reading
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Chronic Liver Diseases and the Microbiome: Translating Our Knowledge of Gut Microbiota to Management of Chronic Liver Disease
Chronic liver disease is reaching epidemic proportions with the increasing prevalence of obesity, non-alcoholic liver disease, and alcohol overuse worldwide. Most patients with are not candidates for liver transplantation, even if they have end-stage l… Continue reading
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Somatic non-epigenetic mismatch repair gene aberrations underly most mismatch repair-deficient Lynch-like tumors
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Functional Gastrointestinal Disorders and the Microbiome: What is the best strategy for moving microbiome-based therapies for functional gastrointestinal disorders into the clinic?
There have been numerous human studies reporting associations between the intestinal microbiome and functional gastrointestinal disorders (FGIDs), and independently animal studies have explored microbiome-driven mechanisms underlying FGIDs. However, th… Continue reading
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Recurrent Clostridioides difficile infection is associated with impaired Th17 immunity to TcdB
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