Monthly Archives: December 2020
mTORC1 and mTORC2 converge on the Arp2/3 complex to promote KrasG12D-induced acinar-to-ductal metaplasia and early pancreatic carcinogenesis
Oncogenic KrasG12D induces neoplastic transformation of pancreatic acinar cells through acinar-to-ductal metaplasia (ADM), an actin-based morphogenetic process, and drives pancreatic ductal adenocarcinoma (PDAC). mTOR (mechanistic target of rapamycin k… Continue reading
Colonic epithelial-derived Selenoprotein P is the source for antioxidant-mediated protection in colitis-associated cancer
Patients with inflammatory bowel disease (IBD) demonstrate nutritional selenium deficiencies and are at greater risk for colon cancer. Previously, we determined that global reduction of the secreted antioxidant selenium-containing protein, Selenoprotei… Continue reading
VUMC acquires Tennova’s Shelbyville and Tullahoma hospitals from CHS, and is now partnered with Tennova Clarksville Hospital
Leaders of Vanderbilt University Medical Center announced today the acquisition of Tennova Healthcare-Shelbyville and Tennova Healthcare-Harton hospitals and their related businesses, including physician clinic operations and outpatient services, from … Continue reading
A “Healthier You” webinar: Top Coronavirus Questions Answered
UT Southwestern’s Rosen up next in Discovery Lecture Series, Jan. 14
Michael Rosen, PhD, professor and chair of Biophysics at the University of Texas Southwestern Medical Center, will discuss mysterious cellular compartments known as “biomolecular condensates” during the next web-based Discovery Lecture. Continue reading
Important reminder: Report 2020 contributions to outside retirement plans by April 1, 2021
Health Sciences Education Grand Rounds on educational quality improvement set for Jan. 11
Vanderbilt Digestive Disease Research Center retreat set for Jan. 5
First-person essay: Doing my part to end the pandemic
Kevin Johnson, MD, MS, FAAP, FACMI: The Rev. Martin Luther King, Jr. once said, “Our lives begin to end the day we become silent about things that matter.” In that spirit, please allow me to be vocal, opinionated, hopeful and forgiving. Continue reading