Daily Archives: December 8, 2020

Pluripotent Stem Cell-Derived Human Liver Organoids Enter the Realm of High-Throughput Drug Screening

Posted on December 8, 2020 by Gastroenterology Journal
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AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease (NAFLD): Expert Review

Posted on December 8, 2020 by Gastroenterology Journal

Nonalcoholic fatty liver disease. (NAFLD) is a leading etiology for chronic liver disease with global public health impact, affecting over 25% of the global population. NAFLD is associated with significant morbidity and mortality from cirrhosis, hepato… Continue reading →

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Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice

Posted on December 8, 2020 by Gastroenterology Journal

Pancreatic ductal adenocarcinomas (PDAC) are characterized by fibrosis and an abundance of cancer-associated fibroblasts (CAFs). We investigated strategies to disrupt interactions among CAFs, the immune system, and cancer cells, focusing on adhesion mo… Continue reading →

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Probiotics and the Microbiome: How can we help patients make sense of probiotics?

Posted on December 8, 2020 by Gastroenterology Journal

The notion of probiotics as microbes that confer health benefits has its origins in the speculative ideas that are more than a century old, yet remain largely unsubstantiated by scientific evidence. The recent advances in microbiome science have highli… Continue reading →

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Protective role of tacrolimus, deleterious role of age and comorbidities in liver transplant recipients with Covid-19: results from the ELITA/ELTR multi-center European study.

Posted on December 8, 2020 by Gastroenterology Journal

Despite concerns that liver transplant (LT) recipients may be at increased risk of unfavorable outcomes from COVID-19 due the high prevalence of co-morbidities, immunosuppression and ageing, a detailed analysis of their effects in large studies is lacking Continue reading →

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The gastrointestinal tract is an alternative route for SARS-CoV-2 infection in a nonhuman primate model

Posted on December 8, 2020 by Gastroenterology Journal

Gastrointestinal (GI) manifestations have been increasingly reported in Coronavirus Disease 2019 (COVID-19) patients. However, the roles of the GI tract in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection are not fully understood…. Continue reading →

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Longitudinal Changes in Fecal Calprotectin Levels among Pregnant Women with and without Inflammatory Bowel Disease and Their Babies

Posted on December 8, 2020 by Gastroenterology Journal

The effect of pregnancy on inflammatory bowel disease (IBD) remains poorly understood. We aimed to monitor intestinal inflammation using fecal calprotectin (FC) in pregnant women and their babies during early life. Continue reading →

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Participation in Competing Strategies for Colorectal Cancer Screening – a Randomized Health Services Study (PICCOLINO Study)

Posted on December 8, 2020 by Gastroenterology Journal

Offering a combination of fecal test (FIT) and primary colonoscopy increased participation in colorectal cancer screening compared to colonoscopy alone. Increased participation in combined strategies did not increase detection of target lesions. Continue reading →

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