Daily Archives: January 6, 2021
MiR-10b-5p Rescues Diabetes and Gastrointestinal Dysmotility
Interstitial cells of Cajal (ICCs) and pancreatic β cells require receptor tyrosine kinase (KIT) to develop and function properly. Degeneration of ICCs is linked to diabetic gastroparesis. The mechanisms linking diabetes and gastroparesis are unclear, … Continue reading
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Inflamed ulcerative colitis regions associated to MRGPRX2-mediated mast cell degranulation and cell activation modules, defining a new therapeutic target
Recent literature has implicated a key role for mast cells in murine models of colonic inflammation, but their role in human ulcerative colitis (UC) is not well-established. A major advance has been the identification of mrgprb2 (human orthologue, MRGP… Continue reading
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Abdominal pain and diarrhoea in peptic ulcer disease
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Gastrointestinal Infection and Risk of Microscopic Colitis: A Nationwide Case-Control Study in Sweden
Microscopic colitis is a common cause of diarrhea among older adults. In a nationwide study in Sweden, we found that gastrointestinal infections, particularly from Clostridioides difficile may be a risk factor for microscopic colitis. Continue reading
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