Monthly Archives: March 2021
Elevated liver enzymes, ferritin, CRP, D-dimer, and age are predictive markers of outcomes among Covid-19 African Americans and Hispanic patients
Familial burden and other clinical factors associated with various types of cancer in individuals with Lynch syndrome
Lynch syndrome (LS) is associated with increased risks of various gastrointestinal, gynecologic, genitourinary, and other cancers. Many clinical practice guidelines recommend that LS carriers’ screening strategies be devised based on their family histo… Continue reading
Artificial Sweeteners and Whole-food Science: Could Mice Help Clinicians Make Diet Recommendations for IBD Patients?
Epigenetic Regulation of Intestinal Stem Cells and Disease: A Balancing Act of DNA and Histone Methylation
Genetic mutations or regulatory failure underlies cellular malfunction in many diseases including colorectal cancer (CRC) and Inflammatory bowel diseases (IBD). However, mutational defects alone fail to explain the complexity of such disorders. Epigene… Continue reading
Correction
Gotfried J, Naftali T, Schey R et al. Role of cannabis and its derivatives in gastrointestinal and hepatic disease. Gastroenterology 2020; 159:62–80. Continue reading
Correction
Shah SC, McKinley M, Gupta S, et al. Population-based analysis of differences in gastric cancer incidence among races and ethnicities in individuals age 50 years and older. Gastroenterology 2020; 159: 1705–1714.e2. Continue reading
The Evolution of Biologics Administration From Intravenous to Subcutaneous: Treatments for Inflammatory Bowel Disease Goes Home
Deleterious variants in ABCC12 are detected in idiopathic chronic cholestasis and cause intrahepatic bile duct loss in model organisms
The etiology of cholestasis remains unknown in many children. We surveyed the genome of children with chronic cholestasis for variants in genes not previously associated with liver disease and validated their biological relevance in zebrafish and murin… Continue reading