Monthly Archives: April 2021

AGA Clinical Practice Guidelines on Intragastric Balloons in the Management of Obesity

This document represents the official recommendations of the American Gastroenterological Association (AGA) and was developed by the AGA Clinical Guideline Committee and approved by the AGA Governing Board. Development of this guideline was fully funde… Continue reading

Posted in News | Comments Off on AGA Clinical Practice Guidelines on Intragastric Balloons in the Management of Obesity

No Association Between Endoscopic Screening and Gastric Cancer Incidence in Asian Countries

Posted in News | Comments Off on No Association Between Endoscopic Screening and Gastric Cancer Incidence in Asian Countries

Reply to: Letter to the Editor: Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data

Posted in News | Comments Off on Reply to: Letter to the Editor: Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data

To the Editors:

Posted in News | Comments Off on To the Editors:

IN MEMORIAM

Posted in News | Comments Off on IN MEMORIAM

In Memoriam for Donald O. Castell, M.D.

Posted in News | Comments Off on In Memoriam for Donald O. Castell, M.D.

Intestinal Sulfation is Essential to Protect Against Colitis and Colonic Carcinogenesis

Sulfation is a conjugation reaction essential for numerous biochemical and cellular functions in mammals. The 3′-phosphoadenosine 5′-phosphosulfate (PAPS) synthase 2 (PAPSS2) is the key enzyme to generate PAPS, which is the universal sulfonate donor fo… Continue reading

Posted in News | Comments Off on Intestinal Sulfation is Essential to Protect Against Colitis and Colonic Carcinogenesis

A Liquid Biopsy Assay for Noninvasive Identification of Lymph Node Metastases in T1 Colorectal Cancer

We recently reported use of tissue-based transcriptomic biomarkers (miRNA or mRNA) for identification of lymph node metastasis (LNM) in patients with invasive submucosal colorectal cancers (T1 CRC). In this study, we translated our tissue-based biomark… Continue reading

Posted in News | Comments Off on A Liquid Biopsy Assay for Noninvasive Identification of Lymph Node Metastases in T1 Colorectal Cancer

Epithelia-sensory neuron crosstalk underlies cholestatic itch induced by lysophosphatidylcholine

Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of anti-pruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus. Continue reading

Posted in News | Comments Off on Epithelia-sensory neuron crosstalk underlies cholestatic itch induced by lysophosphatidylcholine

BCL3 couples cancer stem cell enrichment with pancreatic cancer molecular subtypes

The existence of different subtypes of pancreatic ductal adenocarcinoma (PDAC) and their correlation with patient outcome have shifted the emphasis on patient classification for better decision-making algorithms and personalized therapy. The contributi… Continue reading

Posted in News | Comments Off on BCL3 couples cancer stem cell enrichment with pancreatic cancer molecular subtypes