Daily Archives: August 29, 2021

PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis

Posted on August 29, 2021 by Gastroenterology Journal

Oral therapies targeting the integrin α4β7 may offer unique advantages for treatment of inflammatory bowel disease. We characterized the oral α4β7 antagonist peptide PTG-100 in preclinical models, and established safety, pharmacokinetic/pharmacodynamic… Continue reading →

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