Daily Archives: August 30, 2021

LTE Reply to 21-00786 and 21-01414

Posted on August 30, 2021 by Gastroenterology Journal
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The tight junction protein ZO-1 is dispensable for barrier function but critical for effective mucosal repair

Posted on August 30, 2021 by Gastroenterology Journal

S AND AIMS: Increased permeability is implicated in the pathogenesis of intestinal disease. In vitro and in vivo studies have linked downregulation of the scaffolding protein ZO-1, encoded by the TJP1 gene, to increased tight junction permeability. Thi… Continue reading →

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