Daily Archives: September 29, 2021

Epithelial XBP1 coordinates TP53-driven DNA damage responses and suppression of intestinal carcinogenesis

Welz et al. show that XBP1 coordinates epithelial stem cell function in response to DNA damage in a mechanism involving the tumor suppressor TP53. Continue reading

Posted in News | Comments Off on Epithelial XBP1 coordinates TP53-driven DNA damage responses and suppression of intestinal carcinogenesis

Serologic response to coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated inflammatory diseases: a systematic review and meta-analysis

Patients with immune-mediated inflammatory diseases (IMIDs) have an increased risk of COVID-19, primarily attributed to the use of immunosuppressive drugs such as glucocorticoids, which may attenuate the response to vaccines. This meta-analysis aims to… Continue reading

Posted in News | Comments Off on Serologic response to coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated inflammatory diseases: a systematic review and meta-analysis