Monthly Archives: September 2021
AGA Clinical Practice Update on Endoscopic Surveillance and Management of Colorectal Dysplasia in Inflammatory Bowel Diseases: Expert Review
Improvements in disease management, as well as endoscopic technology and quality, have dramatically changed the way in which we conceptualize and manage inflammatory bowel disease–related dysplasia over the past 20 years. Based on evolving literature, … Continue reading
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miR-802 Suppress Acinar-to-Ductal Reprogramming during Early Pancreatitis and Pancreatic Carcinogenesis
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive tumor that is almost uniformly lethal in humans. Activating mutations of KRAS are found in >90% of human PDACs and are sufficient to promote acinar-to-ductal metaplasia (ADM) during tumor i… Continue reading
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GPR120 inhibits colitis through regulation of CD4+T cell IL-10 production
G protein-coupled receptor (GPR) 120 has been implicated in regulating metabolic syndromes with anti-inflammatory function. However, the role of GPR120 in intestinal inflammation is unknown. Here, we investigated whether and how GPR120 regulates CD4+T … Continue reading
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Clinical Challenges and Images in GI – “Not What You Think?”
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Food for Thought: Consumption of a High Fat Diet in Combination with Antibiotics Results in Early Inflammatory Changes in the Gastrointestinal Tract
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Durability of Endoscopic Eradication Therapy for Barrett’s Esophagus Related Neoplasia: A Call for Centralized Care
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Adenoma detection Rates for 45-49 year old screening population
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Genomic and molecular analyses identify molecular subtypes of pancreatic cancer recurrence
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MUC5AC serves as the nexus for β-catenin/c-Myc interplay to promote glutamine dependency during pancreatic cancer chemoresistance
A major clinical challenge for pancreatic cancer (PC) patients is metabolic adaptation. Neoplastic cells harboring molecular perturbations suffice for their increased anabolic demand and nucleotide biosynthesis to acquire chemoresistance. The mucin 5AC… Continue reading
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