Daily Archives: October 7, 2021

Uniting the Global Gastroenterology Community to Meet the Challenge of Climate Change and Non-Recyclable Waste

Posted on October 7, 2021 by Gastroenterology Journal

Climate change has been described as the biggest global health threat of the 21st century1 and has significant implications for gastrointestinal (GI) health and disease,2 which is the focus of this consensus commentary provided by the World Gastroenter… Continue reading →

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Activating Immune Recognition in Pancreatic Ductal Adenocarcinoma via Autophagy Inhibition, MEK blockade and CD40 Agonism

Posted on October 7, 2021 by Gastroenterology Journal

Pancreatic ductal adenocarcinoma (PDA) patients have not yet benefitted from the revolution in cancer immunotherapy due in large part to a dominantly immunosuppressive tumor microenvironment (TME). MEK inhibition combined with autophagy inhibition lead… Continue reading →

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CME Exam 1: The Tight Junction Protein ZO-1 Is Dispensable for Barrier Function But Critical for Effective Mucosal Repair

Posted on October 7, 2021 by Gastroenterology
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Host-microbiota interactions in the esophagus during homeostasis and allergic inflammation

Posted on October 7, 2021 by Gastroenterology Journal

Microbiota composition and mechanisms of host-microbiota interactions in the esophagus are unclear. Herein, we aimed to uncover fundamental information about the esophageal microbiome and its potential significance to eosinophilic esophagitis (EoE). Continue reading →

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Incidence and mortality in upper gastrointestinal cancer after negative endoscopy for gastroesophageal reflux disease

Posted on October 7, 2021 by Gastroenterology Journal

Gastroesophageal reflux disease (GERD) is associated with an increased risk of cancer of the upper gastrointestinal tract. This study aimed to assess whether and to what extent a negative upper endoscopy in patients with GERD is associated with a decre… Continue reading →

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