Daily Archives: October 20, 2021

HLA Class I analysis provides insight into the genetic and epigenetic background of immune evasion in colorectal cancer with high microsatellite instability.

Posted on October 20, 2021 by Gastroenterology Journal

A detailed understanding of antitumor immunity is essential for optimal cancer immune therapy. Although defective mutations in the B2M and HLA-ABC genes, which encode molecules essential for antigen presentation, have been reported in several studies, … Continue reading →

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Prolonged impairment of short-chain fatty acid and L-isoleucine biosynthesis in gut microbiome in patients with COVID-19

Posted on October 20, 2021 by Gastroenterology Journal

SARS-CoV-2 infection is associated with altered gut microbiota composition. Phylogenetic groups of gut bacteria involved in the metabolism of short chain fatty acids were depleted in SARS-CoV-2-infected patients. We aimed to characterize functional pro… Continue reading →

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Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell–Fibroblast Crosstalk

Posted on October 20, 2021 by Gastroenterology Journal

Eosinophilic esophagitis (EoE) can progress to fibrostenosis by unclear mechanisms. Herein, we investigated gene dysregulation in fibrostenotic EoE, its association with clinical parameters and specific pathways, and the functional consequences. Continue reading →

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Comparing colorectal cancer screening outcomes in the International Cancer Screening Network (ICSN): A Consortium proposal

Posted on October 20, 2021 by Gastroenterology Journal
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Connecting the dots: Dietary fat, microbiota dysbiosis, altered metabolome and colon cancer

Posted on October 20, 2021 by Gastroenterology Journal
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