Daily Archives: October 29, 2021
Abnormal TP53 predicts risk of progression in patients with Barrett’s esophagus regardless of a diagnosis of dysplasia.
Barrett’s esophagus (BE) is the precursor to esophageal adenocarcinoma. A major challenge is identifying the small group with BE who will progress to advanced disease from the many who will not. Assessment of p53 status has promise as a predictive biom… Continue reading
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An unpredictable cause of gastrointestinal bleeding
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Efficacy of biologic drugs in short-duration versus long-duration inflammatory bowel disease: A systematic review and an individual-patient data meta-analysis of randomized controlled trials
Starting biologic treatment early in the course of inflammatory bowel disease (IBD) may associate with higher efficacy, especially in Crohn’s disease (CD). Continue reading
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Colorectal Cancer in Inflammatory Bowel Disease: Mechanisms and Management
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Cellular Plasticity, Reprogramming, and Regeneration: Metaplasia in the Stomach and Beyond
The mucosa of the body of the stomach (i.e., the gastric corpus) employs two overlapping, depth-dependent mechanisms to respond to injury. Superficial injury heals via surface cells with histopathological changes like foveolar hyperplasia. Deeper, usua… Continue reading
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