Daily Archives: November 12, 2021
An integrated taxonomy for monogenic inflammatory bowel disease
Monogenic forms of inflammatory bowel disease (IBD) illustrate the essential roles of individual genes in pathways and networks safeguarding immune tolerance and gut homeostasis. Continue reading
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Integrative analysis of the Inflammatory Bowel Disease serum metabolome improves our understanding of genetic etiology and points to novel putative therapeutic targets
Polygenic and environmental factors are underlying causes of inflammatory bowel disease (IBD). We hypothesized that integration of the genetic loci controlling a metabolite’s abundance, with known IBD genetic susceptibility loci, may help resolve metab… Continue reading
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