Monthly Archives: November 2021

Mentoring disparities in gastroenterology: the path forward

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Protective Role of Spermidine in Colitis and Colon Carcinogenesis

Because inflammatory bowel disease is increasing worldwide and can lead to colitis-associated carcinoma (CAC), new interventions are needed. We have shown that spermine oxidase (SMOX), which generates spermidine (Spd), regulates colitis. Here we determ… Continue reading

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Off-therapy response after nucleos(t)ide analogue withdrawal in patients with chronic hepatitis B: An international, multi-center, multi-ethnic cohort (RETRACT-B study)

Functional cure, defined by hepatitis B surface antigen (HBsAg) loss, is rare during nucleos(t)ide analogue (NA) therapy and guidelines on finite NA therapy have not been well established. We aim to analyze off-therapy outcomes following NA cessation i… Continue reading

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CME Exam 3: COVID-19 Vaccination in Patients with Immune-Mediated Inflammatory Diseases

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COVID-19 Vaccination Is Associated with Reduced SARS CoV2 Infection and Death in Liver Transplant Recipients

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Donor screening for fecal microbiota transplantation in China: Evaluation of 8,483 candidates

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Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients with Crohn’s Disease

Mirikizumab is a humanized monoclonal antibody targeting IL-23p19 with demonstrated efficacy in psoriasis and ulcerative colitis. We investigated the safety and efficacy of mirikizumab in patients with moderate-to-severe Crohn’s disease (CD). Continue reading

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Correction

Jin B, Ha SE, Wei L, et al. Colonic Motility Is Improved by the Activation of 5-HT2B Receptors on Interstitial Cells of Cajal in Diabetic Mice. Gastroenterology 2021;161:608–622. Continue reading

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CME Exam 2: Global Incidence of Acute Pancreatitis is Increasing Over Time: A Systematic Review and Meta-Analysis

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Early Transplantation for Alcohol-Related Cirrhosis: Risks, Resources, and Relapse

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