Monthly Archives: November 2021
Mentoring disparities in gastroenterology: the path forward
Protective Role of Spermidine in Colitis and Colon Carcinogenesis
Because inflammatory bowel disease is increasing worldwide and can lead to colitis-associated carcinoma (CAC), new interventions are needed. We have shown that spermine oxidase (SMOX), which generates spermidine (Spd), regulates colitis. Here we determ… Continue reading
Off-therapy response after nucleos(t)ide analogue withdrawal in patients with chronic hepatitis B: An international, multi-center, multi-ethnic cohort (RETRACT-B study)
Functional cure, defined by hepatitis B surface antigen (HBsAg) loss, is rare during nucleos(t)ide analogue (NA) therapy and guidelines on finite NA therapy have not been well established. We aim to analyze off-therapy outcomes following NA cessation i… Continue reading
CME Exam 3: COVID-19 Vaccination in Patients with Immune-Mediated Inflammatory Diseases
COVID-19 Vaccination Is Associated with Reduced SARS CoV2 Infection and Death in Liver Transplant Recipients
Donor screening for fecal microbiota transplantation in China: Evaluation of 8,483 candidates
Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients with Crohn’s Disease
Mirikizumab is a humanized monoclonal antibody targeting IL-23p19 with demonstrated efficacy in psoriasis and ulcerative colitis. We investigated the safety and efficacy of mirikizumab in patients with moderate-to-severe Crohn’s disease (CD). Continue reading
Correction
Jin B, Ha SE, Wei L, et al. Colonic Motility Is Improved by the Activation of 5-HT2B Receptors on Interstitial Cells of Cajal in Diabetic Mice. Gastroenterology 2021;161:608–622. Continue reading