Daily Archives: December 23, 2021

Inhibition of p53 sulfoconjugation prevents oxidative hepatotoxicity and acute liver failure

Sulfoconjugation of small molecules or protein peptides is a key mechanism to ensure biochemical and functional homeostasis in mammals. The PAPS synthase 2 (PAPSS2) is the primary enzyme to synthesize the universal sulfonate donor 3′-phosphoadenosine 5… Continue reading

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The maze of systemic therapy for hepatocellular carcinoma: did we find the compass?

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Surveillance imaging in individuals at high-risk for pancreatic cancer: Not a ceiling, but rather a floor upon which to build

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Gut microbiome metabolism drives the resolution of patients with COVID-19

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