Daily Archives: December 28, 2021
Intestinal Cathelicidin Antimicrobial Peptide Shapes a Protective Neonatal Gut Microbiota against Pancreatic Autoimmunity
Alteration of the gut microbiota is implicated in the development of autoimmune type 1 diabetes (T1D), as shown in humans and the non-obese diabetic (NOD) mouse model. However, how gut dysbiosis arises and promotes the autoimmune response remains an op… Continue reading
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Clonal transitions and phenotypic evolution in Barrett esophagus
Barrett esophagus (BE) is a risk factor for esophageal adenocarcinoma but our understanding of how it evolves is poorly understood. We investigated BE gland phenotype distribution, the clonal nature of phenotypic change and how phenotypic diversity pla… Continue reading
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