Monthly Archives: January 2022
How do we predict a patient’s disease course and whether they will respond to specific treatments?
Gastroenterologists will be all too familiar with the difficult decisions that managing IBD often presents. How aggressively should I treat this patient? Do I expect them to have a mild or aggressive form of disease? Do they need a biologic? If so, whi… Continue reading
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The future of precision medicine to predict outcomes and control tissue remodeling in inflammatory bowel disease
Inflammatory bowel disease is characterised by significant interindividual heterogeneity. With a wider selection of pharmacological and non-pharmacological interventions available and in advanced developmental stages, a priority for the coming decade i… Continue reading
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Twenty-first century trends in the global epidemiology of pediatric-onset inflammatory bowel disease: systematic review
The incidence of inflammatory bowel disease (IBD) is increasing internationally, particularly in nations with historically low rates. Previous reports of the epidemiology of pediatric-onset IBD identified a paucity of data. We systematically reviewed t… Continue reading
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Inhibition of Viral Replication Reduces Transcriptionally Active Distinct Hepatitis B Virus Integrations with Implications on Host Gene Dysregulation
Hepatocellular carcinogenesis of hepatitis B virus (HBV) infection may arise from integration of viral DNA into the host genome. We aimed to gauge the effect of viral inhibition on transcriptionally active HBV-host integration events and explore the co… Continue reading
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