Daily Archives: February 24, 2022

Mucin 5AC-mediated CD44/ITGB1 clustering mobilizes adipose-derived mesenchymal stem cells to modulate pancreatic cancer stromal heterogeneity

Secreted mucin 5AC from pancreatic tumor systemically modulates adipose-derived mesenchymal stem cells and contributes towards stromal heterogeneity. Understanding Muc5ac-associated fibrotic phenotype may significantly impact the clinical outcomes of a… Continue reading

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Higher vs Standard Adalimumab Induction and Maintenance Dosing Regimens for Treatment of Ulcerative Colitis: SERENE UC Trial Results

SERENE UC evaluated the efficacy of higher adalimumab induction and maintenance dose regimens in patients with ulcerative colitis (UC). Continue reading

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Esophageal Motility Disorders: Current Approach to Diagnostics and Therapeutics

Dysphagia is a common symptom with significant impact on quality of life. Our diagnostic armamentarium was primarily limited to endoscopy and barium esophagram until the advent of manometric techniques in the 1970s, which provided the first reliable to… Continue reading

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