Monthly Archives: April 2022
A chromosomal duplication encompassing IL-33 causes a novel Hyper IgE phenotype characterized by eosinophilic esophagitis and generalized autoimmunity.
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Clinical applications of artificial intelligence in gastroenterology: excitement and evidence
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Databases for GI Clinical and Public Health Research: Have Database, Will Research
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β-Catenin sustains and is required for YES-associated protein oncogenic activity in cholangiocarcinoma
YAP aberrant activation is implicated in intrahepatic cholangiocarcinoma (iCCA). TEAD mediated transcriptional regulation is the primary signaling event downstream of YAP. The role of Wnt/β-Catenin signaling in cholangiocarcinogenesis remains undetermi… Continue reading
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An uncommon cause of coffee ground emesis in a young woman with remote Roux-en-Y gastric bypass
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Toll Like Receptor 9 Pathway Mediates Schlafen+-MDSC Polarization During Helicobacter-Induced Gastric Metaplasias
A subset of MDSCs that express murine Schlafen4 (SLFN4) or its human ortholog SLFN12L polarize in the Helicobacter-inflamed stomach coincident with intestinal or spasmolytic polypeptide-expressing metaplasia (SPEM). We propose that individuals with a m… Continue reading
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Gastroenterology: A New Editorial Team Coming to You From Around the World
We assume leadership of Gastroenterology with a blend of humility, trepidation, and excitement. There have been many eminent Editors-in-Chief of Gastroenterology, including our immediate predecessors, Richard M. Peek, Jr, MD, AGAF, and Douglas A. Corle… Continue reading
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Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer
The gastrointestinal hamartomatous polyposis syndromes are rare, autosomal dominant disorders associated with an increased risk of benign and malignant intestinal and extraintestinal tumors. They include Peutz-Jeghers syndrome, juvenile polyposis syndr… Continue reading
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Prediction models for celiac disease development in children from high-risk families: Data from the PreventCD cohort
Screening for celiac disease (CD) is recommended in children with affected first-degree relatives (FDR). However, the frequency of screening and at what age remain unknown. Aims:to detect variables influencing the risk of CD-development and develop and… Continue reading
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A Distinct and Potentially Deadly Cause of Gastric Polyposis
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